Search details
1.
Exome sequencing and analysis of 454,787 UK Biobank participants.
Nature
; 599(7886): 628-634, 2021 11.
Article
in English
| MEDLINE | ID: mdl-34662886
2.
Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.
J Lipid Res
; 55(8): 1693-701, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-24891332
3.
Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.
J Lipid Res
; 53(1): 51-65, 2012 Jan.
Article
in English
| MEDLINE | ID: mdl-22021650
4.
In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS.
J Lipid Res
; 52(1): 159-69, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20884843
5.
siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids.
J Lipid Res
; 52(6): 1084-1097, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21398511
6.
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo.
J Lipid Res
; 52(1): 78-86, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20959675
7.
Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.
J Proteome Res
; 10(10): 4683-91, 2011 Oct 07.
Article
in English
| MEDLINE | ID: mdl-21819150
8.
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Nat Genet
; 53(7): 942-948, 2021 07.
Article
in English
| MEDLINE | ID: mdl-34183854
9.
Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens.
J Biomol Screen
; 13(5): 378-89, 2008 Jun.
Article
in English
| MEDLINE | ID: mdl-18480473
10.
Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Biochem Pharmacol
; 71(4): 453-63, 2006 Feb 14.
Article
in English
| MEDLINE | ID: mdl-16325781
11.
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.
Science
; 354(6319)2016 Dec 23.
Article
in English
| MEDLINE | ID: mdl-28008009
12.
Increased hypercholesterolemia and atherosclerosis in mice lacking both ApoE and leptin receptor.
Atherosclerosis
; 181(2): 251-9, 2005 Aug.
Article
in English
| MEDLINE | ID: mdl-16039278
13.
Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement.
ACS Med Chem Lett
; 6(5): 553-7, 2015 May 14.
Article
in English
| MEDLINE | ID: mdl-26005532
14.
Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors.
Assay Drug Dev Technol
; 1(6): 777-87, 2003 Dec.
Article
in English
| MEDLINE | ID: mdl-15090224
15.
A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format.
Assay Drug Dev Technol
; 1(6): 789-800, 2003 Dec.
Article
in English
| MEDLINE | ID: mdl-15090225
16.
The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans.
Circ Cardiovasc Genet
; 6(1): 54-62, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23243195
17.
An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
Int J Biol Sci
; 8(3): 310-27, 2012.
Article
in English
| MEDLINE | ID: mdl-22355267
18.
ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5).
Lipids
; 46(11): 991-1003, 2011 Nov.
Article
in English
| MEDLINE | ID: mdl-21826528
19.
Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry.
J Am Soc Mass Spectrom
; 22(9): 1552-67, 2011 Sep.
Article
in English
| MEDLINE | ID: mdl-21953258
20.
Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network.
Genome Res
; 19(6): 1057-67, 2009 Jun.
Article
in English
| MEDLINE | ID: mdl-19261841